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骨髓间充质干细胞神经分化条件及分化机制 被引量：1

Condition and mechanisms of neural differentiation in bone marrow mesenchymal stem cells
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摘要 骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSC)作为中胚层来源的多能干细胞,除了能够分化为间充质系细胞如成骨细胞、脂肪细胞和软骨细胞外,尚具有神经分化的潜能,可望用于治疗神经退行性病变,而对于BMSC的神经分化条件及机制的充分了解能够更好的指导研究,故本文在此对BMSC的神经分化条件及机制进行综述。 Bone marrow mesenchymal stem cells（BMSC）are a kind of multipotential cells in mesoderm.With exception of differentiating mesenchymal cells like osteoblasts,adipocytes and chondrocytes,BMSC have the potential of neural differentiation and can be used to treat neurodegeneration.A good understanding for the condition and mechanisms of neural differentiation in BMSC can be used to guide study.This article reviews the condition and mechanisms of neural differentiation in BMSC.
作者 王海燕 苏冠方 徐春玲
机构地区 吉林大学第二医院眼科
出处 《眼科新进展》 CAS 北大核心 2009年第12期955-958,共4页 Recent Advances in Ophthalmology
基金 国家自然科学基金资助(编号:30471858)~~
关键词 骨髓间充质干细胞 神经分化 基因 信号通路 bone marrow mesenchymal stem cells neural differentiation gene signal pathway
分类号 R77 [医药卫生—眼科]
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参考文献38

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同被引文献9

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  • 9牟大鹏,苏冠方,徐春玲,王世瑶,王心蕊.骨髓间充质干细胞向视网膜神经节样细胞的诱导分化[J].眼科新进展,2009,29(2):94-97. 被引量：5

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眼科新进展
2009年 第12期

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