白癜风凝胶对豚鼠实验性白癜风治疗作用

Curative Effect of Vitiligo Gel on Experimental Vitiligo Models

目的观察白癜风凝胶对豚鼠实验性白癜风的疗效。方法用化学脱色法制备实验性白癜风动物模型,用白癜风凝胶进行治疗,并与白癜风酊的疗效进行比较,以表皮毛囊黑素生成、胆碱酯酶和酪氨酸酶活性为考察指标。结果白癜风凝胶比白癜风酊对白癜风动物的黑素生成、胆碱酯酶和酪氨酸酶的活性影响更显著。结论白癜风凝胶比白癜风酊对实验性白癜风有更好的治疗作用。

Objective To study the curative effect of vitiligo gel on experimental guinea pig models of vitiligo. Methods The animal models of vitiligo were prepared by chemical decolour method, then treated with vitiligo gel and tincture as control. AMMC, activity of acetylcholine esterase and tyrosinase were detected. Results The vitiligo gel showed better effects than vitiligo tincture on the formation of AMMC and the activity of acctylcholine esterase and tyrosinase. Conclusion The vitiligo gel has good effects on experimental vitiligo models over vitiligo tincture.