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替米沙坦对高血压患者胱抑素及C反应蛋白的影响 被引量:2

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摘要 目的观察替米沙坦治疗高血压时对C反应蛋白(CRP)及胱抑素(CysC)水平的影响。方法原发性高血压1级和2级患者100例,随机分成两组,治疗组和对照组各50例。治疗组给予替米沙坦,每天20~80mg,po,对照组给予氨氯地平,每天2.5~10mg,po。疗程均8周,比较两组血压、CRP及CysC的变化。结果两组治疗前各项指标差异无显著性(P>0.05);经过8周的治疗,两组CRP、CysC和血压较治疗前均有明显好转(P<0.01);治疗组的CRP及CysC较对照组改善明显(P<0.05)。结论替米沙坦降压的同时有可能减轻炎性反应,延缓肾功能损害。
出处 《医药导报》 CAS 2010年第1期46-48,共3页 Herald of Medicine
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