摘要
厌氧菌为体内主要的正常菌群,为条件致病菌,在局部或全身抵抗力下降时才发生侵入和感染,厌氧菌可致多系统感染,可单独致病,也可与需氧菌协同致病,其治疗十分棘手,继60年代研究发现,甲硝唑(Metronidazole灭滴灵)对厌氧菌具有强大杀伤力后,甲硝唑被广泛应用于临床,疗效确切,同时其副作用也逐渐被认识。
Anaerobe,a main flora normally existing in human body,is conditionally pathogenic.Only when resistance to bacteria in part of or the whole body reduces,does anaerobe invade the body,causing infection.Multisystem infection,caused by anaerobe alone or anaerobe together with aerobe,is very hard to treat.Since its strong destroying power on anaerobe was found in 1960s,metronidazole has been widely used in clinical treatment.Its definite curative effect has been proved and its side effect gradually known.
关键词
厌氧菌
甲硝唑
临床应用
副作用
anaerobe
metronidazole
clinical application
side effect