新疆乌鲁木齐地区汉族与维吾尔族绝经后女性骨质疏松患者发病特点的研究

The research of the characteristics of osteoporosis after menopause in han and uygur ethnic population in Urumqi

目的探讨新疆乌鲁木齐地区汉族与维吾尔族绝经后女性骨质疏松患者发病特点。方法将确诊为绝经后女性骨质疏松症患者汉族(118例),维吾尔族(39例)进行分组,分析对比两组患者骨密度测定值,骨特异性碱性磷酸酶(BAP)、骨钙素(BGP)、抗酒石酸酸性磷酸酶5b(TRACP-5b)、1-(OH)维生素D3以及血清Ca、P、Mg水平。结果维吾尔族女性原发性骨质疏松症患者发病年龄小于汉族患者,维吾尔族女性原发性骨质疏松症患者的绝经年龄早。维吾尔族1-(OH)维生素D3水平明显低于汉族组(P<0.01),骨钙素(BGP)检测值维吾尔族原发性骨质疏松症患者高于汉族(P<0.05)。结论维吾尔族原发性骨质疏松症患者,可能与汉族有着不同的骨质疏松症发病机制。维吾尔族原发性骨质疏松症患者更应补充足量的活性维生素D。

Objective To study the characteristics of osteoporosis after menopause in Han ethnic and Uygur ethnic population in Urumqi. Methods To compare 118 Han patients of osteoporosis with Uygur ethnic and analyze the BMD,and BAP,BGP, TRACP-5b,1-（OH）vitD3 ,Ca,P,Mg in serum. Results It was different that compare the age of occurrence of osteoporosis in Han ethnic to Uygur ethnic population in Urumqi. The menopause occurring in Uygur ethnic is earlier than Han ethnic. The mean level of 1-（OH） vitD3 of Uygur ethnic was significantly lower than that of ethnic groups（ P 〈 0.01 ）, and the mean level of BGP was higher than that of Han ethnic groups（ P 〈 0.05）. Conclusion It was different that the characteristics of occurrence of osteoporosis in Han ethnic and Uygur ethnic population in Urumqi. We advise that Uygur ethnic population with osteoporosis have more vitD3 .