^(125)碘粒子钛镍合金支架在梗阻性直肠癌治疗中的应用

Ni-Ti rectal tent with 125-iodine radionuclide used in treatment of obstructive rectal carcinoma

目的:探讨125碘粒子钛镍合金支架治疗直肠癌梗阻的疗效和意义。方法:45例直肠癌并梗阻的患者,在内镜及X线辅助下进行直肠内125碘粒籽钛镍合金支架治疗。结果:45例患者直肠内125碘粒籽钛镍合金支架置入均获成功,手术前后体质量、血常规中白细胞计数、中性粒细胞和血小板计数比较差异无统计学意义,P>0.05;卡氏评分分别为68.5±4.0、86.4±11.5,两者比较差异具有统计学意义,P=0.002;随访3个月未发现严重并发症。结论:直肠内125碘粒籽钛镍合金支架治疗作为直肠癌术前梗阻解除或晚期复发肿瘤的姑息治疗均能达到梗阻解除、避免肠造瘘术、改善患者生活质量的效果。

OBJECTIVE：To study the curative effect and significanceof Ni-Ti rectal tent with 125-iodine radionuclide in rectum in the treatment of obstruction of rectum cancer patients.METHODS：Forty-five rectum cancer patients with obstruction were treated by putting Ni-Ti rectal tent with 125-iodine radionuclide in the rectum.The changes about weight,blood routine,Karnosfsky and complications were observed.RESULTS：The successful treatments were observed,and there was a statistically significanct difference about Karnosfsky between the pre-operation and post-operation（68.5±4.0 vs 86.4±11.5,P=0.002）.On the contrary,the difference was below the level of statistical significance about weight and blood routine including white blood cells,neutrophil and platelet counts.There were no important complications in the treatment group.CONCLUSION：Ni-Ti rectal tent with 125-iodine radionuclide has a curative effect and safety in the treatment of advanced rectal carcinoma.