期刊文献+

烧伤后患者增生性瘢痕细胞凋亡异常的机制研究

原文传递
导出
摘要 众多研究表明,凋亡异常在增生性瘢痕的形成与发展中发挥着重要作用。肿瘤坏死因子相关的凋亡诱导配体(the TNF-related apoptosis—inducing ligand,TRAIL)是继肿瘤坏死因子和FASL之后发现的第三个肿瘤坏死因子超家族中的凋亡分子,它在体内行使重要的免疫监视功能,当其与受体结合后,能快速有效地诱导体内异常细胞的凋亡,而对大多数正常的组织细胞没有毒性。为此,我们探讨了TRAIL-TRAIL受体系统在烧伤后患者增生性瘢痕凋亡异常中的作用。
机构地区 青岛市江苏路
出处 《中华整形外科杂志》 CAS CSCD 北大核心 2009年第6期472-473,共2页 Chinese Journal of Plastic Surgery
  • 相关文献

参考文献6

二级参考文献26

  • 1Mieke L, Mieke B, Maria P, et al.Human epidermal keratinocytes are a source of tenascin-c during wound healing.J Invest Dermato, 1997, 108:776-783.
  • 2Andriessen MP, Niessen FB, Van de Kerkhof PC, et al.Hypertrophic scarring is associated with epidermal abnormalities: an immunohistochemical study.J Pathol, 1998, 186:192-200.
  • 3Betz P, Nerlich A, Wllske J, et al.The time-dependent localization of Ki-67 antigen positive cell in human skin wound.Int J Legal Med, 1995, 106:35-40.
  • 4Kurt W, Chen L, Prediman K, et al.Tenascin-c is expressed in macrophage-rich human coronary atherosclerotic plaque.Circulation, 1999, 99:1284-1289.
  • 5Curzio RR, Ruth CE, Sefic SA.Tenascin, an ECM protein, exerts immunomodulatory activities.Cell Biol, 1989, 86:7437-7441.
  • 6Latijnhouwers MA, Bergers M, Van Bergen BH, et al.Tenascin expression during wound healing in human skin.J Pathol, 1996, 178:30-35.
  • 7Filsell W, Rudman S, Jenkins G, et al.Coordinate upregulation of tenascin-c expression with degree of photodamage in human skin.Brit J Derm, 1999, 140:592-599.
  • 8Richard PT, James AH, David AJ, et al.Tenascin expression in the mouse: in situ localization and induction in vitro by bFGF.J Cell Sci, 1993, 104:69-76.
  • 9Saed GM, Ladin D, Olson J, et al.Analysis of p53 gene mutation in keloids using polymerase chain reaction-based single-strand conformational polymorphism and DNA sequencing.Arch Dermatol, 1998, 134:963-968.
  • 10Desmouliere A, Redard M, Darby I, et al. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol, 1995,146:56-66.

共引文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部