异氟醚经氧合器吸入在体外循环手术麻醉中的效果观察

THE EFFECT OBSERVATION ON ISOFLURANE INHALED THROUGH OXYGENATOR IN ANESTHESIA DURING CARDIOPULMONARY BYPASS OPERATION

目的:探讨心内直视手术快通道麻醉方法。方法:对68例体外循环心内直视手术的患者随机分为两组。观察组34例,异氟醚采用自行设计的氧合器吸入的方法进行麻醉;对照组34例,则常规大剂量芬太尼的方法行静脉麻醉。观察其对机体单位体表面积耗氧量(VO2)、平均动脉压最高值(PMAP)、动脉血氧饱和度(SaO2)和心肺复苏的影响,并统计患者的ICU监护时间、住院时间及住院费用,两组进行比较,评估临床效果。结果:观察组与对照组之间VO2、SaO2、PMAP、住院时间,心肺复苏情况比较没有明显差异(P)0.05);苏醒时间、ICU监护时间、住院费用比较具有显著差异(P<0.05或0.01)。结论:异氟醚经氧合器吸入麻醉方法是一种麻醉平稳、安全可靠、且缩短患者苏醒时间,节省住院费用的简便易行的快通道麻醉方法。

Objective：To experiment with the method of fast-track anesthesia in endocardial operation under direct vision.Methods：Sixty-eight patients were randomly divided into the experimental group of 34 cases under going inhalation of isoflurane through the self-designed oxygenator and the contrast group of 34 case receiving the routine large dosage use of fentanyl through intravenous injection.The effects of the two methods on oxygen consumption,the highest value of average arterial pressure,the degree of blood oxygen saturation and the cardio pulmonar）, resuscitation were observed. The montitoring time of patients in ICU, the hospitalization time and the hospitalization expenditure were statistically compared and analyzed. Results：There existed no significant differences between the two roups in terms of oxygen consumption, arterial pressure, degree of blood oxygen saturation, hospitalization time, cardio - jpulmonary functional recovery （P 〉 O. 05 ） , while there existed remarkable difference in terms of the time of resuscitation, the monitoring time in ICU and the hospitalization expenditure （P 〈 0. 05or0.01 ）. Conclusion： Isoflurane inhalation through our self - designed oxygenator can shorten the time of resuscitation and reduce the hospitalization expenditure in addition to its safety and reliability.