1Brandtzaeg P, Berstad AE, Farstad IN. Mucosal immunity-a major adaptive defence mechanism [ J]. Behring Inst Mitt 1997, 98:1.
2Wang D, Christopher ME, Nagata LP, et al. lntranasal immunization with liposome-encapsulated plasmid DNA encoding influenza virus hemagglutinin elicits mucosal, cellular and humoral immune responses[J]. J Clin V iro 1 2004, 31 (Suppll) :S99 - 106.
3Gallichan WS, Rosenthal KL. Long-term immunity and protection against herpes simplex virus type 2 in the murine female genital tract after mucosal but not systemic immunization[ J]. J Infect Dis 1998,177:1155 - 1161.
4Isaka M, Yasuda Y, Kozuka S, et al. Induction of systemic and mucosal antibody responses in mice immunized intranasally with aluminium-non-adsorbed diphtheria toxoid together with recombinant cholera toxin B subunit as an adjuvant[J]. Vaccine 1999,18:743 - 751.
6Horwitz MA, Harth G, Dillon BJ. Recombinant bacillus Calmette- Gu rin (BCG) vaccines expressing the Mycobacterium tuberculosis 30kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model [ J ]. Microbiology 2000,97 : 13853 - 13858.
7Heritage PL, Underdown BJ, Arsenauh AL, et al. Comparison of murinenasal-associated lymphoid tissue and Peyer's patches[J]. Am J Respir Crit Care Med 1997,156:1256 - 1262.
8Chen LH, Wang J, Zganiacz A, et al. Single intranasal mucosal Myeobacterium boris BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosis[J]. Infect lmmun 2004,72( 1 ) :238 - 246.
9Dullars M. A T cell-dependent mechanism for the induction of human mueosal homing immunoglobulin A-secreting plasmablast [J]. Immunity 2009,30( 1 ) :120 - 129.
10Wu HY, Nkolova EB, Beagly KW, et al. In duction of antibodysecreting cells and T-helper and memory cells in murine nasa1 lymphoid tissue [J]. J Immunol 1996,88 (4):493 -500.
