期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

IL-23和IL-17在结核病中的研究进展 被引量：7

下载PDF
导出
摘要 近年来结核病的发病率越来越高,随着对结核病免疫机制的进一步研究,发现了Th17、IL-23、IL-17在结核免疫保护中起着重要作用。对这免疫途径的研究有利于进一步阐明结核病的免疫机制和指导临床诊疗。
作者 游文霞 胡学强
机构地区 中山大学附属第三医院神经病学科
出处 《微生物学免疫学进展》 2009年第4期60-61,共2页 Progress In Microbiology and Immunology
关键词 结核病 IL-23 IL-17
分类号 R52 [医药卫生—内科学]
  • 相关文献

参考文献20

  • 1Global Tuberculosis Control: surveillance, planning, financing [ R ]. WHO Report 2007. Geneva, World Health Organization ( WHO/HTM/TB/2007. 376 ).
  • 2Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17- producing-CD4 + effector T cells develop via a liesgc distinct from the T helper type 1 and lineages [ J ]. Nat Immunol 2005, 6 (11): 1123-1132.
  • 3Weaver CT, Harringt on LE, Mangan PR, et al . Th17: an effector CD4 T cell lineage with regulatory T cell ties[ J]. Immunity 2006, 24 (6) : 677 - 688.
  • 4Mangan PR, Harrington LE, O' Quinn DB, et al. ransforming growth factor-beta induces development of the T (H) 17 lineage[J]. Nature 2006, 441 (7090) : 231 - 234.
  • 5Verreck FA, de Boer T, Langenberg DM,et al. Human IL-23-produeing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to ( myco ) bacteria [ J ]. PNAS 2004, 101 (13) :4560 - 4565.
  • 6Khader S, Pearl J, Sakamoto K, et al. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available [ J ]. J lmmunol 2005, 175 : 788 - 795.
  • 7Khader SA, Cooper AM. IL-23 and IL-17 in tuberculosis[ J]. Cytokine 2008, 41 (2) :79 - 83.
  • 8Chackerian AA, Chen SJ, Brodie SJ,et al. Neutralization or Absence of the Interleukin-23 Pathway Does Not Compromise Immunity to Mycobacterial Infection [ J ]. Infect Immun 2006, 74 (11) :6092 -6099.
  • 9Happel K, Lockhart E, Mason C, et al. Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs [ J ]. Infect lmmun 2005, 73 : 5782 - 5788.
  • 10Aggarwal S, Ghilardi N, Xie MH,et al. Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17 [ J ]. J Biol Chem 2003, 278 (3) : 1910 - 1914.

同被引文献69

  • 1巫顺秀,陈显光,李森美,杜登青,王文莉.脑脊液γ-干扰素检测对结核性脑膜炎诊断价值的探讨[J].华中医学杂志,2006,30(1):41-42. 被引量：14
  • 2王凯旋,韦翊,胡轶,徐敏慧.中枢神经系统感染患儿脑脊液中sICAM-1、IL-6、IFN-γ检测的临床意义[J].浙江医学,2006,28(11):916-917. 被引量：1
  • 3熊思东.抗感染免疫[M]//周光炎.免疫学原理.上海:上海科学技术出版社,2007:244-256.
  • 4Khadcr SA, Cooper AM. IL-23 and IL-17 in tuberculosis [J]. Cytokine, 2008, 41(2): 79-83.
  • 5Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults [J]. N Engl J Med, 2004, 351(17): 1741-1751.
  • 6Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing-CD4+ effector T cells develop via a liesge distinct from the T helper type 1 and lineages [J]. Nat Immtmol, 2005, 6 (11): 1123-1132.
  • 7Khader SA, Bell GK, Pearl JE, et al. IL-23 and IL-17 in establishment of protective pulmonary CD4+ T cell responses upon vaccination and during Mycobacterium tuberculosis challenge [J], Nat Immunol, 2007, 8(4): 369-377.
  • 8Kleinschek MA, Muller U, Brodie S J, et al. IL-23 erthanees the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12 [J]. J Immunol, 2006, 176(2): 1098-1106.
  • 9Kleinschek MA, Muller U, Schutze N, et al. Administration of IIJ-23 engages innate and adaptive immune mechanisms during fungal infection[J]. Int Immunol, 2010, 22(2): 81-90.
  • 10Zelante T, De Luca A, Bonifazi P, et al. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance [J]. Eur J lmmunol, 2007, 37(10): 2695-2706.

引证文献7

二级引证文献26

微生物学免疫学进展
2009年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部