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调节性T细胞抑制作用机制的研究进展 被引量：1

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摘要 调节性T细胞(Treg)对维持机体免疫动态平衡具有重要作用。不仅诱导产生自身免疫耐受,防止自身免疫疾病的发生,而且能够限制免疫防御中T、B细胞过度活化,避免造成组织损伤。最近研究发现,Treg可能导致效应性免疫细胞失活,降低机体对肿瘤和病原的免疫应答。尽管Treg可能通过调节免疫细胞活化、增值和分化及效应等多环节产生抑制作用,但其抑制机制仍未清楚。本文对近几年国外研究Treg可能的抑制作用机制的进展作一综述。
作者 王嘉军 张伟
机构地区 三峡大学医学院病原生物学部
出处 《微生物学免疫学进展》 2009年第4期62-65,共4页 Progress In Microbiology and Immunology
关键词 调节性T细胞 抑制 机制
分类号 R392.12 [医药卫生—免疫学]
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参考文献35

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同被引文献8

  • 1屠小卿,仲人前,范列英,朱烨,袁媛,季玲燕.自身免疫性肝病患者血清转化生长因子β_1测定的临床意义[J].检验医学,2004,19(5):427-428. 被引量：1
  • 2张莹,姚咏明,盛志勇.调节性T细胞研究进展[J].生理科学进展,2007,38(1):83-88. 被引量：17
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微生物学免疫学进展
2009年 第4期

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