木瓜蛋白酶对补骨脂有效成分煎出的影响

Study on the Influence of Papain to the Extraction of EffectiveComponent of Fructus Psoraleae

利用木瓜蛋白酶预处理补骨脂粉后煎提，与普通煎煮法比较，煎液总氮量提高了２倍，磷脂提高了４倍；补骨脂素、异补骨脂素提高了近１倍。结果提示，蛋白酶水解蛋白质的同时，促进了磷脂的溶出，发挥增溶作用，最终导致各种有效成分煎出量增加。

This paper reported the comparision study of two kinds of decocting method of Fructus Psoraleae, i.e. general decocting and pretreatment with papain before decocting. The result showed that the contents of nitrogen, phospholipid, psoralene and isopsoralene in extractive papain pretreatment increased 2 times, 4 times, nearly 1 time, respectively.