摘要
为探讨多种介入治疗方法并用对恶性胆道梗阻病人的疗效,对35例恶性胆道梗阻病人进行分析。35例病人中10例采用胆道外引流加局部动脉化疗栓塞治疗,19例采用胆道外引流、支架植入及动脉化疗栓塞联合治疗,6例行外引流及胆管内保留灌注化疗治疗。结果:35例胆道外引流及19例支架植入均获成功,减黄效果显著。29例动脉化疗栓塞病人显示了肯定的抗瘤效应,而6例胆管内保留灌注化疗病人未显示抗瘤作用。两者死亡病例平均生存期分别为8.5月和3.5月,两组比较有显著性差异(P<0.05)。结论:胆道支架植入和/或外引流与局部动脉化疗栓塞联合应用是治疗恶性胆道梗阻的安全有效的综合疗法。
To evaluate the effectiveness of combined interventional procedures for treatment of malignant biliary obstructions, we analysed 35 patients with nonresectable malignant biliary obstruction. Ten of them were treated with PTCD and transcatheter artery infusion chemotherapy or embolization (TAI/TAE), nineteen treated with PTCD, TAI/TAE and stent implantation; six treated with PTCD and intrabiliary infusion chemotherapy (BIC). The results showed that twentynine cases treated with TAI/TAE showed satisfactory anticancer results, nevertheless 6 cases treated with BIC showed no curative effects. In comparison of mean survival of died patients in two groups, statistic differences could be seen (8.5 months versus 3.5 months). The results suggest that stent implantation and/or PTCD combined with TAI/TAE is one of the safe and effective methods for treatment of malignant biliary obstructions. Effect of BIC is indefinite and further trials are needed.
出处
《中国普通外科杂志》
CAS
CSCD
1998年第4期220-222,共3页
China Journal of General Surgery
关键词
胆道肿瘤
胆管阻塞
介入治疗
栓塞疗法
Biliary tract neoplasms Bile duct obstruction Biliary tract surgery Embolization,therapeutic