脑脊液置换结合活血化瘀中药治疗脑出血破入脑室30例疗效观察

Observation on therapeutic efficacy of cerebral spinal fluid displacement combined use of Huoxue Huayu recipe on 30 patients with cerebral hemorrhage ruptured into cerebral ventricle

目的：观察脑脊液置换结合活血化瘀中药治疗脑出血破入脑室患者的疗效。方法：脑出血患者６０例随机分为２组，每组均为３０例。治疗组采用一般治疗加脑脊液置换及活血化瘀中药治疗；对照组采用一般治疗和脑脊液置换。结果：治疗组治愈率４０．０％，总有效率８３．３％，无变化、恶化和病死率１６．７％；对照组治愈率２３．３％，总有效率６３．３％，无变化、恶化和病死率３６．７％。治疗组疗效明显优于对照组（Ｐ＜０．０５）。复查ＣＴ示脑实质内血肿全部吸收时间，治疗组为７日～４６日，平均２３日，对照组为１５日～７０日，平均５０日，脑实质内血肿吸收速度２组比较有显著性差异（Ｐ＜０．０５）。结论：脑脊液置换结合活血化瘀中药治疗脑出血破入脑室，可提高患者生存质量，降低病死率和致残率。

Objective:To observe the effect of cerebral spinal fluid (CSF) displacement combined use of Huoxue Huayu recipe in treating cerebral hemorrhage (CH) ruptured into cerebral ventricle.Methods:Sixty cases of CH were divided randomly into 2 groups:treatment group (n=30) was treated with CSF displacement and Huoxue Huayu recipe on the basis of conventive therapy;control group (n=30) was treated with conventive therapy and CSF displacement.Results:In the treatment group,cured rate was 400%,total effective rate was 833%,ineffective,deteriorate and death were 167%;in the control group,cured rate was 233%,total effective rate was 633%,ineffective,deteriorate and death were 367%,so the therapeutic efficacy in treatment group was better obviously than control group (P<005).Moreover,CT reexamine suggested that complete absorption time of cerebral hematoma was 7 to 46 days (mean 23 days) in treatment group and 15 to 70 days (mean 50 days) in control group,there have obvious difference between 2 groups (P<005).Conclusions:CSF displacement combined use of Huoxue Huayu recipe treating CH ruptured into cerebral ventricle can raise life quality and decrease mortality and disability rate.