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40岁以下青年食管癌的外科治疗与预后分析 被引量:2

Treatment and Prognosis of Patients Under 40 Years of Age with Esophageal Carcinoma
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摘要 目的探讨青年食管癌的外科治疗效果及影响其预后的因素。方法回顾性分析36例40岁以下青年食管癌的临床资料。全组患者均经手术治疗,其中经左胸30例,经右胸6例。结果总的3、5年生存率分别为32.1%和23.0%。单因素分析显示肿瘤T分期、淋巴结转移状况、病变长度、手术性质、TNM分期为影响预后的主要因素;而多因素分析显示肿瘤T分期、淋巴结转移是影响预后最重要的独立因素。结论青年食管癌临床分期较晚,根治性手术切除率较低,应加强早诊治意识;肿瘤T分期、淋巴结转移是影响预后的最重要因素。 Objective To assess the treatment and prognosis of patients under 40 years of age with esophageal carcinoma. Methods The data of 36 patients were analyzed retrospectively. Curative resection was performed on all patients, including through-Left-thorax resection (30) and through-right-thorax resection (6). Results The overall 3- and 5-year survival rates were 32. 1% and 23.0% of the whole group respectively. T stage, lymph node metastasis, length of the tumors, operative types( radical resection or non-radical resection) and TNM stage were the main factors that affected the prognosis. Conclusion In young patients with esophageal carcinoma, the clinical stage is later, and the radical resection rate is lower. Early detection and treatment are crucial to improving the survival rate. Lymph node metastasis and T stage were the independent prognostic factors.
出处 《肿瘤基础与临床》 2009年第5期418-420,共3页 journal of basic and clinical oncology
关键词 青年 食管肿瘤 外科手术 预后 young esophageal carcinoma surgical procedures prognosis
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  • 1戎铁华,林鹏,吴一龙.胸段食管癌淋巴结转移的临床研究(附220例分析)[J].中华胸心血管外科杂志,1994,10(3):242-244. 被引量:57
  • 2张焱,高剑波,程敬亮,杨涛,李荫太,张战利,卢国庆,任翠萍,赵艺蕾,周志刚.术前CT及MRI检查判别食管癌外侵主动脉的价值[J].郑州大学学报(医学版),2006,41(1):152-153. 被引量:2
  • 3[1]Nygaard K, Hagen S, Hansen HS, et al. Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma:a randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer [J]. World J Surg, 1992, 16(6): 1104- 1110.
  • 4[2]Wang M, Gu XZ, Yin WB, et al. Randomized clinical trial on the combination of preoperative irradiation and surgery in the treatment of esophageal carcinoma: report on 206 patients [J].Int J Radiat Oncol Biol Phys, 1989, 16 (2): 325 -327.
  • 5[3]Gignoux M, Roussel A, Paillot B, et al. The value of preoperative radiotherapy in esophageal cancer: results of a study by the EORTC [J]. Recent Results Cancer Res, 1988, 110:1 -13.
  • 6[4]Bosset JF, Gignoux M, Triboulet JP, et al. Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus [J]. N Engl J Med, 1997, 17, 337(3):161 - 167.
  • 7[5]Le Prise E, Etienne P L, Meunier B, et al. A randomized study of chemotherapy, radiation therapy and surgery versus surgery for localized squamous cell carcinoma of the esophagus [J]. Cancer,1994, 73:1779 - 1784.
  • 8[6]Apinop C, Puttisak P, Preecha N. A prospective study of combined therapy in esophageal cancer [J]. Hepatogastroenterology, 1994, 41(4): 391-393.
  • 9[7]Hennequin C, Gayet B, Sauvanet A, et al. Impact on survival of surgery after concomitant chemoradiation for locallyadvanced cancers of the esophagus [J]. Int J Radiat Oncol Biol Phys,2001, 49:657-664.
  • 10[8]Slater MS, Holland J, Faigel DO, et al. Does neoadjuvant chemoradiation downstage esophageal carcinoma? [J]. Am J Surg, 2001, 181: 440-444.

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