急性脑梗塞患者血糖糖化血红蛋白水平与梗塞灶大小的关系

Relationship between the levels of blood sugar、GHb and the size of focus infarct in patients with acute cerebral infarct

目的研究急性脑梗塞患者血糖、糖化血红蛋白水平与梗塞灶大小及临床预后之间的关系。方法９６例急性脑梗塞患者入院５ｄ内查头颅ＣＴ，计算梗塞灶体积，起病７２小时内空腹或静脉输液前测定血糖及糖化血红蛋白。将血糖升高组（ｎ＝４４），糖化血红蛋白升高组（ｎ＝２６）梗塞灶大小及好转率、死亡率与血糖及糖化血红蛋白正常组（ｎ＝５２）进行比较。统计学处理采用ｔ检验和χ２检验。结果血糖升高组、糖化血红蛋白升高组梗塞灶较血糖正常组明显增大，呈显著性差异，血糖升高组好转率低于血糖正常组，死亡率高于血糖正常组。结论急性脑梗塞患者血糖升高尤其伴糖化血红蛋白升高者，梗塞灶大，脑水肿严重。

Objective To research the relationship between the levels of blood sugar,GHb and the size of focus infarct.Mehtod All 96 cases of acute cerebral infarct were examined with skull CT within 5d after admission for calcualting volume of focus of infarct.The levels of fasting blood sugar and GHb were measured within 72h after attacking.The size of focus infarct,favorable rate and mortality rate were comparied with normal blood sugar group.The t test and chi-square test were used for statistical analysis.Results The size of focus infarct in high blood sugar and GHb group were laarger than that of normal blood sugar group.The mortality rate in high blood sugar and high GHb group were higher than that of normal blood sugar group.Conclusion The higher the levels of blood sugar and GHb the larger the size of cerebral infarction.The levels of blood sugar and GHb are related with prognosis of cerebral infarction.