尿激酶治疗急性心肌梗死的应用研究

[tudy on urokinase on patients with acute myocardium infarction

目的：探讨尿激酶静脉溶栓治疗急性心肌梗死患者的临床疗效和安全性。方法：将73例急性心肌梗死患者随机分为观察组（38例）和对照组（35例），观察组采用尿激酶治疗，对照组采用肝素治疗，比较两组患者的疗效。结果：冠状动脉再通率、出血并发症、心律失常和病死率均优于对照组，二者差异存在显著性（P〈0．05）。结论：尿激酶静脉溶栓治疗急性心肌梗死疗效显著。安全可靠，易于在基层医院推广。

Objective： To explore the clinical curative effect and safety of intravenous injection urokinasc on patients with acute myocardium infarction. Methods ：73 patients acute myocardium infarction were divided randomly into the intervention group （38 eases） and the contrul group （35 eases）, the intervention group was treated with urokinase, while the control group was treated with heparin, and then the effects of two groups were compared. Results：The re -open rate of infarct related artery,the complication of hemorrhage rate,the arrhythmia rate and the death rate in the intervention group were better than the latter, there were significant differences between two groups （P 〈 0.05 ）. Conclusion： Intravenous injection urokinase on patients with acute myocardium infarction is evident effective and high safe, it may be generalized in substrate hospital.