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抗菌药物耐药突变选择窗的研究进展 被引量：3

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作者 李静 时东彦 赵建宏
机构地区 河北医科大学第二医院检验科河北省临床检验中心 秦皇岛海港医院检验科
出处 《临床荟萃》 CAS 2010年第2期164-167,共4页 Clinical Focus
基金 国家科技基础条件平台工作重点项目(2005DKA21202-6) 河北省卫生厅医学重点课题(08075)
关键词 抗生素 抗药性 微生物 突变 药代动力学
分类号 R987.1 [医药卫生—药品]
  • 相关文献

参考文献27

  • 1Zhao X, Drlica K. Restricting the selection of antibioticresistant mutants: a general strategy derived from fluoroquinolone studies[J]. Clin Infect Dis, 2001,33 (Suppl 3) : 147-156.
  • 2Zhao X, Drlica K. Restricting the selection of antibioticresistant mutants: measurement and potential uses of themutant selection window[J]. J Infect Dis, 2002, 185(4): 561-565.
  • 3Dong Y, Zhao X, Domagala J, et al. Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus [J ]. Antimicrob Agents Chemother, 1999,43(7) :1756-1758.
  • 4Davidson R, Cavalcanti R, Brunton JL, et al. Resistance to levofloxacin and failure of treatment of pneumococeal pneumonia[J]. N Engl J Med,2002,346(10):747-750.
  • 5Sieradzki K, Leski T, Dick J, et al. Evolution of a vancomycinintermediate Staphylococcus aureus strain in vivo: multiple changes in the antibiotic resistance phenotypes of a single lineage of methicillin-resistant S. aureus under the impact of antibiotics administered for chemotherapy [ J ]. J Clin Microbiol, 2003,41 (4) : 1687-1693.
  • 6Howden BP, Stinear TP, Allen DL, et al. Genomic analysis reveals a point rnntation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus[J]. Antimicrob Agents Chemother, 2008,52 (10):3755- 3762.
  • 7Zhou J ,Dong Y, Zhao X, et al. Selection of antibiotic resistant bacterial mutants: allelic diversity among fluoroquinoloneresistant mutations[J]. J Infect Dis, 2000,182 (2) :517 -525.
  • 8Sindelar G, Zhao X, Liew A, et al. Mutant prevention concentration as a measure of fluoroquinolone potency against mycobacteria [J]. Antimicrob Agents Chemother, 2000, 44 (12) :3337-3343.
  • 9Li X, Mariano N. Rahal JJ, et al. Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin[J]. Antimicrob Agents Chemother, 2004, 48 (11) :4460 -4462.
  • 10Quinn B, Hussain S, Malik M, et al. Daptomycin inoculum effects and mutant prevention concentration with Staphylococcus aureus [J]. J Antimicrob Chemother, 2007,60 (6) : 1380-1383.

二级参考文献20

  • 1谢林,刘晓东,王大为.注射用阿奇霉素的生物利用度研究[J].江苏药学与临床研究,2004,12(3):12-14. 被引量：1
  • 2崔俊昌,刘又宁,王睿,梁蓓蓓,裴斐,郑专杰.4种氟喹诺酮类药物对金黄色葡萄球菌的防耐药变异浓度[J].中华医学杂志,2004,84(22):1863-1866. 被引量：34
  • 3童卫杭,柴栋,崔俊昌,陈锟,王睿.兔感染性模型组织液中左氧氟沙星浓度HPLC测定[J].中国抗生素杂志,2005,30(12):759-761. 被引量：6
  • 4崔俊昌,刘又宁,王睿杭,童卫杭,李朝霞.左氧氟沙星对兔组织笼金黄色葡萄球菌感染的疗效研究[J].中国临床药理学与治疗学,2007,12(3):291-294. 被引量：7
  • 5[1]Zhao X,Drlica K.Restricting the selection of antibiotic-resistant mutants:a general strategy derived from fluoroquinolones studies.Clin Infect Dis,2001,33(Suppl):S147-S156.
  • 6[2]Drlica K.The mutant selection window and antimicrobial resistance.J Antimicrob Chemother,2003,52:11-17.
  • 7[6]Croisier D,Etienne M,Bergoin E,et al.Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy.Antimicrob Agents Chemother,2004,48:1699-1707.
  • 8[7]Croisier D,Etienne M,Piroth L,et al.In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia:impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants.J Antimicrob Chemother,2004,54:640-647.
  • 9[8]Etienne M,Croisier D,Charles PE,et al.Effect of low-level resistance on subsequent enrichment of fluoroquinolone-resistant Streptococcus pneumoniae in rabbits.J Infec Dis,2004,190:1472-1475.
  • 10Drlica K.The mutant selection concentration and antimicrobial resistance[J].J Antimicrob Chemotherk,2003;52:11-17.

共引文献18

同被引文献15

引证文献3

二级引证文献1

临床荟萃
2010年 第2期

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