西藏林芝地区藏族健康体检人群高尿酸血症分析

Hyperuricemia in Tibetans Undergoing Health Examination in Linzhi District in Tiebet

目的了解西藏林芝地区藏族人群高尿酸血症的患病情况,为防治高原高尿酸血症和相关疾病提供依据。方法采用尿酸酶法对在某院体检的2867例藏族健康体检者的血尿酸水平进行测定,分析比较不同年龄段(≤30岁、31～40岁、41～50岁、≥51岁)、不同性别血尿酸水平及高尿酸血症检出率。结果2867例中高尿酸血症782例(27.3%);男性646(22.50%),女性136例(4.74%),男女高尿酸血症检出率之比为4.75∶1,男性明显多于女性(χ2=85.5,P<0.01)。2867例血尿酸水平平均为(369.7±126.8)μmol/L,其中男性、女性血尿酸水平分别为(389.4±141.5)μmol/L和(316.7±89.5)μmol/L,男性明显高于女性(t=16.4,P<0.05)。结论林芝地区藏族人群高尿酸血症发病率高,严重危害了藏族群众的健康,应该引起高度重视,同时应针对藏族饮食和民族特点开展健康教育以预防和控制高尿酸血症和相关疾病的发生。

Objective To explore the hyperuricemia prevalence of Tibetans in Linzhi district in Tibet and to supply reference for preventing hyperuricemia and associated diseases. Methods Uricase method was utilized to detect the blood uric acid levels of the 2867 healthy Tibetans undergoing physical exmamination in a hospital. The serum uric acid levels and prevalence of hyperuricemia were compared among different age groups （≤30 years old, 31 to 40 years old,41 to S0 years old, ≥51 years old ） and different genders. Results In 2867 cases, 782 cases （27. 3%） had hyperuricemia, inclu ding 646 males （22. 50%）, and 136 females （4. 74%）. The prevalence ratio of hyperlipidemia was 4. 75：1 for men and women, significantly higher in men than in women （X^2 = 85.5, P〈0. 01）. The average blood uric acid level was （379. 7 ± 126. 8） μmol/L in 2867 cases, （389. 4 ± 141.5）μmol/L in men and （316. 7 ± 89. 5）μmol/L in women, significantly higher in men than in women （t = 16. 4,P〈0. 05）. Conclusion There is high incidence of hyperuricemia in Tibetans and people＇s health is seriously affected in Linzhi district in Tibet. To prevent and control hyperurieemia and associated diseases, great attention should be paid and health education should be carried out according to the national characteristics of Tibetan diet.