早期干预对早产儿脑损伤预后影响的研究

Study on the effect of early intervention on the prognosis of preterm infant with brain injury

目的探讨早期综合干预对脑损伤早产儿体格、智能发育预后的影响。方法选择脑损伤早产儿75例,按照单、双日法,随机分为干预组和对照组。干预组生理功能稳定后,进行早期综合干预训练。于纠正胎龄6个月、12个月时进行体格、发育商检测并评价。结果两组早产儿头围、身长、体重的体格发育在纠正胎龄6个月、12个月时比较,差异均有统计学意义(P<0.05或P<0.01)。两组早产儿的发育商在纠正胎龄6个月、12个月时比较,差异均有统计学意义(P<0.05或P<0.025)。结论早期干预可以明显改善脑损伤早产儿的体格、智能发育。

Objective To explore the effect of early comprehensive intervention on the physical and mental developments in preterm infants with brain injury. Methods Seventy-five cases of preterm infants with brain injury were divided into the intervened group and the controlled group with randomized methods. The intervened group was given early comprehensive intervention training after they were stable physically. Developmental assessments were done at corrected age of six months and 12 months. Results Head circumference, length and weight were measured for all the infants at the corrected age of six months and 12 months. The differences between the two groups were significant statistically （P〈0. 05 or P〈0.01）. And there was significant difference in developmental quotient as well （P〈0.05 or P〈0. 025）. Conclusion Early intervention can improve the physical and mental development in preterm infarcts with brain injury .