高血压脑出血术后脑灌注压与预后的关系研究

Study on the Relationship Between Cerebral Perfusion Pressure and Prognosis in Postoperative Patients with Hypertensive Intracerebral Hemorrhage

【目的】通过研究高血压脑出血术后脑灌注压（CPP）与预后的关系，探讨术后适宜的CPP阈值。 【方法】对87例高血压脑出血手术病人术后CPP进行测定，按CPP值将病人分为3组。其中A组：CPP〈60mmHg；B组：60mmHg≤CPP〈80mmHg；C组：CPP〉80mmHg。术后1个月时对3组病例行GOS评分对预后进行比较。【结果】术后60mmHg≤CPP〈80mmHg的病例组预后要优于其他两组（P〈0．05）。【结论】高血压脑出血术后CPP维持在60-80mmHg阈值范围内的病例预后较好。

[Objective] To study the relationship between cerebral perfusion pressure（CPP） and prognosis in postoperative patients with hypertensive intracerebral hemorrhage, and to determine the suitable threshold of postoperative CPP. [Methods] Eighty seven patients were divided into three groups on the basis of their CPP including Group A with CPP〈60 mmHg, Group B with 60mmHg≤CPP 〈 80 mmHg and Group C with CPP 〉 80mmHg. One month after operation, the prognosis of three groups were compared by Glasgow outcome scale （GOS）. [Results] The prognosis of Group B was better than that of other two groups（ P 〈0. 05） [Conclusion] The CPP in patients with hypertensive intraeerebral hemorrhage after operation should be kept within the range of 60-80 mmHg in order to improve the prognosis.