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老年骨髓增生异常综合征35例临床分析

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摘要 【目的】分析老年骨髓增生异常综合征(MDS)的临床特点,以利于有效诊治。【方法】回顾性分析35例老年MDS病例的临床症状、血常规、骨髓象、细胞形态、细胞化学染色、染色体检查等变化特征。【结果】老年MDS患者有不同程度的贫血、发热、骨痛等症状;并出现病态造血;35例老年MDS病例中,20例发现克隆性染色体异常,异常检出率为57.1%,以数目异常最为常见,其次为染色体长、短臂增加或缺失。【结论】老年MDS造血机能与机体免疫力低下有关,常规治疗措施对本组患者疗效较差。
作者 余蓉晖 彭丹
出处 《医学临床研究》 CAS 2009年第12期2344-2346,共3页 Journal of Clinical Research
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