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TS基因多态性与肿瘤相关研究进展 被引量:3

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出处 《河北医药》 CAS 2009年第24期3410-3412,共3页 Hebei Medical Journal
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参考文献26

  • 1Hori T,Takahashi E, Ayusawa D, et al. Regional assignment of the human thymidylate synthase ( TS ) gene to chromosome band 18p11. 32 by nonisotopic in situ by hybridization. Hum Genet, 1990,85:576-580.
  • 2Iacopetta B, Grieu F, Joseph D, et al. A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil. Br J Cancer,2001, 85:827-830.
  • 3Kazuyuki K, awakami, K, Eiji K, et al. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinalcancer. Anticancer Research, 1999, 19: 3249- 3252.
  • 4Marsh S, Ameyaw MM, Githanga J, et al. Novel thymidylate synthase enhancer region alleles in African populations. Hum Mutat, 2002,16: 528.
  • 5Kaneda S, Nalbantoglu J, Takeishi K. et al. Structural and functional analysis of the human thymidylate synthase gene. J Biol Chem, 1990,265: 20277 -20284.
  • 6Marcuello E, Altes A, Del Rio E, et al. Single nucleotide polymorphism in the 5'tandem repeat sequences of thymidylate ynthase gene predicts for response to fluorouracil-based chemotherapy in dvaneed colorectal cancer patients, int J Cancer,2004,112:733-737.
  • 7Kawakami K,Watanabe G. ldentigication and functional analysis of single nucleotide pulymorphism in the tandem repeat sequence of thymidylate synthase gene. Cancer Res,2003 ,63 :6004-6007.
  • 8Ulrich CM, Bigler J, Velicer CM.et al. Searching expressed sequence tag databases synthase gene. Cancer Epidemiol Biomarkers Prey, 2000,9: 1381-5.
  • 9高长明,吴建中,刘燕婷,丁建华,李苏平,苏平,胡旭,开海涛,Takezaki Toshiro,Tajima Kazuo.胸苷酸合成酶基因多态和生活习惯及亚甲基四氢叶酸还原酶基因协同作用与胃癌的易感性[J].中华流行病学杂志,2003,24(7):599-603. 被引量:16
  • 10Mandola MV, Stochlmacher J, Zhang W, et al. A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels. Pharmacogenetics, 2004,14:319-327.

二级参考文献5

  • 1Marsh S, Collie-Duguid ESR, Li T, et al. Ethnic variation in the thymidylate synthase enhancer region polymorphism among caucasian and Asian population. Genomics, 1999,58 : 310-312.
  • 2Horie N, Aiba H, Oguro K, et al. Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5'-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct, 1995, 20:191-197.
  • 3Ulrich CM, Bigler J. Velicer CM, et al. Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomark Prev,2000,9 : 1381-1385.
  • 4Chen J, Giovannucci E, Kelsey K, et al. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.Cancer Res, 1996,56:4862-4864.
  • 5高长明,吴建中,丁建华,刘燕婷,臧宇,李苏平,苏平,胡旭,徐天亮,Takezaki Toshiro,Tajima Kazuo.亚甲基四氢叶酸还原酶基因C677T多态性与胃癌易感性的关系[J].中华流行病学杂志,2002,23(4):289-292. 被引量:26

共引文献15

同被引文献21

  • 1董稚明,崔雅静,邝刚,王瑞,于凤玲,张健慧.胸苷酸合成酶基因多态性及其蛋白表达与食管鳞状细胞癌淋巴结转移的关系[J].癌症,2005,24(10):1225-1229. 被引量:11
  • 2高长明,陆建伟,吴建中,曹海霞,冯继锋,田岛和雄.胸苷酸合成酶基因3′-UTR多态性与晚期胃癌化疗敏感性关系的研究[J].临床肿瘤学杂志,2005,10(6):580-583. 被引量:7
  • 3宋亮,陈坤,范春红,张薇,金明娟,何寒青,童峰.胸苷酸合成酶基因多态性与结直肠癌易感性的关系[J].中华消化杂志,2006,26(3):155-158. 被引量:4
  • 4Scagliotti GV,Selvaggi G.New data integrating multitargetedantifolates into treatment of first-line and relapsed non-small-cell lung cancer[J].Clin Lung Cancer,2008,9(Suppl 3):S122-S128.
  • 5Scagliotti GV,Parikh P,von PJ,et al.PhaseⅢstudy compa-ring cisplatin plus gemcitabine with cisplatin plus pemetrexedin chemotherapy-naive patients with advanced-stage non-small-cell lung cancer[J].J Clin Oncol,2008,26(21):3543-3551.
  • 6Rossi A,Ricciardi S,Maione P,et al.Pemetrexed in the treat-ment of advanced non-squamous lung cancer[J].Lung Cancer,2009,66(2):141-149.
  • 7Rosell R,Felip E,Paz-Ares L.How could pharmacogenomicshelp improve patient survival[J].Lung Cancer,2007,57(Suppl2):S35-S41.
  • 8Ulrich CM,Bigler J,Velicer CM,et al.Searching expressed se-quence tag databases:discovery and confirmation of a commonpolymorphism in the thymidylate synthase gene[J].CancerEpidemiol Biomarkers Prev,2000,9(12):1381-1385.
  • 9Mandola MV,Stoehlmacher J,Zhang W,et al.A6 bp polymor-phism in the thymidylate synthase gene causes message insta-bility and is associated with decreased intratumoral TS mRNAlevels[J].Pharmacogenetics,2004,14(5):319-327.
  • 10Dotor E,Cuatrecases M,Martinez-Iniesta M,et al.Tumor thy-midylate synthase 1494del6 genotype as a prognostic factor incolorectal cancer patients receiving fluorouracil-based adjuvanttreatment[J].J Clin Oncol,2006,24(10):1603-1611.

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