肾病综合征血清CA125升高的影响因素分析

Influencing factor analysis of the level of serum CA125 in patients with nephrotic syndrome

目的探讨肾病综合征患者中血清CA125升高的影响因素。方法分别统计入选的63例肾病综合征患者的浆膜腔积液情况、年龄、性别、肾病综合征病因、24 h蛋白尿定量、肾小球滤过率等。采用Logistic回归分析可能导致肾病综合征血清CA125升高的相关因素。结果肾病综合征的病因、肾小球滤过率水平、浆膜腔积液情况、透析治疗情况与肾病综合征患者血清CA125升高具有密切相关性。结论肾病综合征患者浆膜腔积液、透析治疗均与血清CA125升高密切相关。

Objective To research the influential factors of the level of serum CA125 in nephrotic syndrome patients. Methods The relevant data of 63 uephrotic syndrome patients were analyzed. The possible correlated factors which induced the elevation of the level of serum CA125 in the nephrotic syndrome patients were determined by logistic regression analysis. Results Etiology of nephrotic syndrome, glomerular filtration rate, dropsy of serous cavity, and dialysis treatment were related to the elevation of the level of serum CA125 in nephrotic syndrome patients. Conclusions The elevation of serum CA125 in nephrotic syndrome patients is not a definite indiation to malignant tumour, and dropsy of serous cavity and dialysis treatment may relate to the elevation of the level of serum CA125.