性传播性尿道炎的诊断与治疗(附62例报告)

Diagnosis and treatment of sexual transmitted urethritis

为探讨一种对性传播性尿道炎有效的诊断和治疗方法，采用病原体培养和聚合酶链反应（PCR）检测62例性传播性尿道炎，结果病原体培养淋球菌（NG）阳性9例，解脲文原体（UU）阳性30例，两者均阳性5例，均阴性18例；沙眼衣原体（CT）阳性25例，UU阳性17例，两者均阳性20例，其中合并NG阳性17例。病原体培养与PCR显示NG和UU双阳性分别为13例和34例，双明性分别为47例和25例，两种方法不一致考分别为2例和3例。PCR对NG和UU的敏感度分别98．3％和97．2％，特异性分别为97.9％和92．6％。所有患者均口服阿奇霉素500mg，每3d1次，总剂量1．5g。结果治愈50例，显效6例，无效6例，有效率为90．3％。提示PCR对CT、UU及NG感染是一种敏感、特异、快捷和无创伤的检测技术，可作为性传播性尿道炎复查常规检测手段。阿奇霉素对治疗性传播世尿道炎具有疗效好、副作用少、服用方便等优点，值得推广应用。

To study a method of diagnosis and treatment of sexual disseminate urethritis, 62 cases were analysed by PCR and culture of pathogen. The positive of culture of pathogen for NG and UU were 9 and 30 cases respectively. Both positive were 5 cases,negative were 18 cases. The positive of PCR 25 and 17 cases for CT and UU,both positive 20 cases,among which 17 cases were complicated with NG, The two methods all positive were 13 cases and 34 cases for NG and UU,respeetively. PCR and culture of pathogen were not identical 3 and 2 cases,respectively. The sensitivity and speciality of PCR for NG and UU were 98. 3% and 94. 2%, 97. 9% and 92. 6%,respectively. Azithromycin was used to all cases. 90. 3% of patients were clinically cured or improved. The results showed suggested that the PCR was sensitive,especilly,rapid,convenient and no hurt for the diagnosis of CT, UU and NG. And Azithromycin was an effective,little side effect and convenient for sexual transmitted urethritis.