摘要
目的:强调乳腺癌患者术后进行合理辅助治疗的重要性。方法:依据中国常见恶性肿瘤诊治规范乳腺癌分册以及有关文献,通过对76例乳腺癌术后2年内复发及转移的原因进行分析,提出预防对策。结果:要防止乳腺癌术后短期复发和转移,应注意以下几个问题:(1)局部切除需彻底,要严格掌握乳腺癌肿块切除术、乳腺单切术的适应证;(2)对Ⅲ期病例术前应进行必要的化疗或放疗;(3)对绝经前腋淋巴结有转移的患者,术后应尽早进行有效的、足量的全身化学药物治疗,以减少远处转移;(4)根据淋巴结转移情况、病变部位加用放射治疗,以减少局部复发。结论:乳腺癌是一种全身性疾病,只有遵照诊治规范进行综合治疗,才有望减少复发,提高生存率。
Objective: To emphasize the rationality of adjuvant treatment in postoperative breast cancer.Methods: According to the Breast Cancer Fascicule (BCF) in the regulation of diagnosing and treating practice for common malignant tumors in China and related documents,the causes of shortterm(2years) relapse and metastasis in seventysix cases with postoperative breast cancer were analyzed.The preventive measures were suggested.Results: In order to prevent short term relapse and metastasis in cases with postoperative breast cancer,the following points of attention should be paid:(1)Indications of various mastectomies should be handled properly;(2)It is necessary that preoperative chemotherapy and radiotherapy should be given for cases with stage Ⅲ disease;(3)Effective and sufficient postoperative chemotherapy should be given as early as possible in premenopausal patients with axillary lymphnode metastasis;(4)Local radiotherapy should be applied to reduce local relapse according to the situation of axillary lymphnode. Conclusions: Breast cancer is a systemic disease,it is not possible to reduce relapse and increase survival except for multidisciplinary therapy in the basis of BCF.