250例小肝癌的手术切除效果

Results of surgical resection on 250 patients withsmall hepatocellular carcinoma

目的：报道２５０例小肝癌手术切除的效果。材料与方法：我院１９６４年１０月至１９９７年１２期间，经手术切除的２５０例直径小于或等于５ｃｍ的小肝癌。结果：手术切除后生存３年以上８９例，５年以上５６例，１０年以上１４例。其术后１、３、５、１０年生存率分别是８９．８％、７２．４％、５６．９％、４５．４％，手术死亡率为１．６％。结论：肝癌切除术是治疗小肝癌最有效的方法。医学影像学的进步、亚临床期小肝癌的增多、小肝癌切除手术的简化、综合治疗的广泛应用以及复发后的再治疗均使小肝癌手术疗效得到提高。

Purpose: To report the results of surgical resection on 250 patients with small hepatocellular carcinoma(SHCC). Methods: 250 patients with SHCC (≤5cm) were treated with surgical resection from October 1964 to December 1997 in our hospital. Results: 89 patients survive more than 3 years, 56 patients 5 years and 14 patients 10 years. The 1-,3-,5- and 10-year survival rates were 89.8,72.4%,56.9% and 45.4% respectively. The operative mortality was 1.6%. Conclusion: Hepatic resection is the most effective method to treat the SHCC. Advance of medical imaging technique, increase of subclinic SHCC, simplification of surgical resection for SHCC, wide use of the limited resection and resection after recurrence are made it possible to improve the therapeutic effect of SHCC.