电子自旋共振研究银杏叶提取物对训练大鼠不同类型肌纤维自由基作用

Effect of Ginkgo Biloba Extract on Free Radicals in Different Fiber Types of Rat Quadriceps by Electron Spin Resonance

用电子自旋共振(ESR)方法研究银杏叶提取物(GBE)对训练大鼠不同类型肌纤维自由基的作用。结果表明,GBE使训练大鼠白肌自由基(gQ=2.0050)显著增强(P<0.05),红肌减弱(P=0.06);使训练大鼠运动力竭后即刻白肌自由基降低74.48%(P<0.005),混合肌降低46.25%(P<0.005),力竭后24h时红肌、混合肌均明显增强(P<0.05)。结果表明:GBE主要促进训练大鼠红肌自由基清除,增强白肌代谢及抗氧化能力,抑制大鼠超强度运动白肌自由基产生,从而延迟运动性疲劳发生。

This study was aiming to investigate the effects of Ginkgo biloba extract （GBE） on free radicals of different fibre types of quadriceps in rats by electron spin resonance （ESR）. Results showed that GBE suspension was able to significantly enhance the intensities of free radical signals （gQ=2.0050） in white muscle of exercise rats （P0.05） while the decrease was observed in red muscles decreased （P=0.06）. However, the intensity was decreased by 74.48% in white muscle （P0.005） and by 46.25% in whole quadriceps （P 0.005） at instant while it was elevated remarkably in red muscle （P 0.05） and whole quadriceps （P0.05） after 24h of strenuous exhaustive exercise. The results showed that GBE could accelerate clearance of free radicals in red muscle and enhance the anti-oxidant activity and exercise tolerance of white muscles.