艾滋病合并马尔尼菲青霉菌感染与常见病原体的鉴别

AIDS Patient Associated with Penicilliosis marneffei and Differentiation with Other Diseases

目的报道1例艾滋病合并马尔尼菲青霉菌病病例,并讨论其与荚膜组织胞浆菌、黑热病杜利小体在骨髓涂片形态学和培养特性的区别。方法分析3种病原体的骨髓形态学及培养特性,找出相互区别的特点。结果艾滋病患者易感染马尔尼菲青霉菌,由于它以分裂方式繁殖,故其在骨髓涂片中及培养方面有特殊的形态结构,不难将其与常见病原体区别开来。结论培养分离出马尔尼菲青霉菌是诊断的金标准,且其在骨髓中的特殊形态对马尔尼菲青霉菌病的诊断有重要意义。

OBJECTIVE To report a case of AIDS associated with penicilliosis marneffei and discriminate the morphology in bone marrow examination and cultural characteristic of Histoplasma capsulatum and Leishmania donovani.METHODS The three pathogens in bone marrow morphology and cultural characteristic were studied.RESULTS AIDS patient was often infected with P.marneffei,but we could differentiated easily from other pathogens because of its breeding by splitting up and the characteristis structure in bone marrow examination.CONCLUSIONS Isolation of the P.marneffei is the golden diagnosis standard,and the examination of bone marrow is important to diagnose P.marneffei infection.