1989-2008年46898例淋病奈瑟球菌涂片检查结果分析

Neisseria gonorrhoeae Smear Test Results:Analysis of 46 898 Cases,1989-2008

目的探讨淋病奈瑟球菌(NG)快速准确的检测方法、流行病学特征及医院感染的控制。方法对1989-2008年来院就诊的46 898例患者做NG涂片检查和部分NG培养及免疫胶乳试验。结果在46 898例涂片中查到细胞内或细胞内外混合型的革兰阴性双球菌764例,阳性率为1.63%;在764例阳性标本中,有721例涂片中发现没有任何杂菌,占镜检阳性总数的94.37%,NG阳性涂片检查有其自身明显特点。结论NG涂片中无杂菌生长且有大量肿胀的中性粒细胞存在时,应特别引起注意,NG涂片检查尤其对中小型社区及乡村医院,尚不能做NG培养、PCR和NG抗原、抗体检测者提供了一条可靠的检验思路。

OBJECTIVE To explore the NG rapid and accurate detection method,epidemiological characteristics and the control of nosocomical infection.METHODS From 1989 to 2008,46 898 patients were under taken the NG smear test,culture and NG immune latex test.RESULTS In the 46 898 cases,764 cases were found out G-diplococci both inside and outside cells or cell.The positive rate was 1.63%.In 764 positive samples,721 cases were not found out other bacteria（94.37%）,NG positive smears had their own features.CONCLUSIONS When no bacteria growth and a large number of swollen neutrophils,particular attention should be paid.NG smears particularly for small media-size community and rural hospitals,without NG culture,PCR and NG antigen/antibody test can be choosed first.