子宫腺肌病与子宫肌瘤的临床对比分析

Comparison of Clinical Characteristics between Adenomyosis and hysteromyoma

目的:探讨子宫腺肌病与子宫肌瘤的临床特点及B超、实验室检测的价值,提高对子宫腺肌病术前的诊断率。方法:选择52例子宫腺肌病患者和62例子宫肌瘤患者为研究对象,并对其临床症状、妇科检查、B超结果及血清CA125水平进行比较。结果:两组患者发病年龄和临床症状相近,但子宫腺肌病的痛经症状明显(P<0.01);妇科检查子宫腺肌病的子宫常均匀性增大,且一般增大<12孕周,而宫体压痛明显高于子宫肌瘤(P<0.01);两组B超诊断符合率分别为61.5%和93.5%,有统计学差异(P<0.01);子宫腺肌病组血清CA125阳性率80.8%,子宫肌瘤组血清CA125阳性率4.8%,有统计学差异(P<0.01)。结论:综合分析子宫腺肌病与子宫肌瘤的临床表现、妇科检查、B超所见和血清CA125水平有助于提高子宫腺肌病的术前诊断。

Objective：To explore the preoperative diagnosis of adenomyosis by comparing the clinical characteristics of adenomyosis and hysteromyoma and investigating the application of ultrasonography B and laboratory tests. Methods： 52 cases of adenomyosis and 62 cases of hysteromyoma were selected. A comparative study was conducted over their ages of the onset, clinical manifestations, results of ultrasound B and levels of serum CA12s. Results： The two groups of pa- tients were similar in age of onset and clinical manifestations. However,dysmenorrhea was more prominent in the group of adenomyosis than in hysteromyoma. There was significant difference （P 〈 0. 01 ）. Physical examine of gynecology showed that uterine enlargement in adenomyosis group was homogeneous and less than enlargement of 12 weeks＂ pregnan- cy and that uterine body tender was more prominent than in hysteromyoma group（P〈0. 01 ）. The accuracies of B--ultr sonic were 61.5 %and 93.5 %for adenomyosis and hysteromyoma, respectively. Such difference was statistically significant （P〈0.01）. In adenomyosis group, the level of serum CA12s was increased evidently and the positive rate was 80. 80%, much higher than that in hysteromyoma group （4.8%, P〈0.01 ）. Conclusions：The diagnosis accuracies of the adenomyosis and hysteromyoma can be improved by analyzing synthetically the clinical characteristics and the laboratory detectons.