正确认识儿童感冒咳嗽药的安全性问题

Correct Understanding on the Safety of Children's Cough and Cold Medicines

目的:为促进儿童感冒咳嗽药的合理使用提供参考。方法:通过对国内外关于儿童使用感冒咳嗽药的安全性的文献及资料的检索和研究,分析儿童使用非处方感冒咳嗽药的有效性、安全性。结果与结论:儿童使用感冒咳嗽药的有效性尚不确定,虽然一系列已报道的严重不良事件和死亡病例尚不能确证是因使用感冒咳嗽药所致,但已说明该类药物对儿童存在巨大健康隐患。针对该类药物品类繁多、使用频繁、家长安全意识不强容易造成剂量误差和重复用药的现状,从生产、流通和使用过程进行监管确有必要。

OBJECTIVE： To provide reference for rational administration of cough and cold medicines （CCMs） for children. METHODS： Through reviewing pertinent literature both at home and abroad, the data about the efficacy, safety and use of over the counter drug CCMs for children and the progress of the relative policy were analyzed. RESULTS ＆ CONCLUSIONS： It has been shown that the CCMs have potential risks for children＇s healthy although no proven evidence has been shown that these drugs are responsible for a series of the serious adverse events and death cases reported in literature. It is urgent to tighten control on the production, circulation and use of these drugs in view of the various drug varieties, frequent use, dosage error and repeated use caused by parents＇ poor sense on drug safety.