期刊文献+

趋化因子CXCL12及其受体CXCR4在口腔癌研究中的进展

Recent Advances of Chemokine CXCL12 and Its Receptor CXCR4 in Oral Cancer Research
下载PDF
导出
摘要 口腔癌是指发生于口腔的恶性肿瘤,包括唇癌、牙龈癌、舌癌、软硬腭癌、颌骨癌、口底癌、涎腺癌和上颌窦癌以及发生于颜面部皮肤黏膜的癌症等。口腔癌是头颈部较常见的恶性肿瘤之一,具有局部侵袭力强.易向颈部淋巴结转移的特点,且颈部淋巴结转移对患者预后影响很大。因此,研究口腔癌的侵袭、转移对提高患者的治愈率和生存率具有重要的意义。
出处 《口腔颌面外科杂志》 CAS 2009年第6期436-439,共4页 Journal of Oral and Maxillofacial Surgery
关键词 口腔癌 CXCL12 CXCR4 肿瘤侵袭 肿瘤转移 oral carcinoma CXCL12 CXCR4 tumor invasion tumor metastasis
  • 相关文献

参考文献22

  • 1康非吾,黄欣,吴正华,温玉明,王昌美.舌鳞状细胞癌颈部淋巴结转移的临床分析[J].口腔颌面外科杂志,2003,13(1):25-27. 被引量:3
  • 2Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis[J]. Nature,2001.410(6824):24-25.
  • 3Ehtesham M, Winston JA, Kabos P. et al. CXCR4 expression mediates glioma cell invasiveness[J]. Oncogene, 2006,25(19):2801-2806.
  • 4Sun YX, Wang J, Shelburne CE, et al. Expression of CXCR4 and CXCL12 (SDF-1) in human prostate eancers(PCa) in vivo[J]. J cell Biochem,2003,89(3):462-473.
  • 5Schitnanski CC, Schwald S. Simiantonaki N, et al. Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human coloreetal cancer[J]. Clin Cancer Res. 2005,11 (5) : 1743-1750.
  • 6Scala S, Ottaiano A, Ascierto P A, et al. Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma[J]. Clin Cancer Res, 2005,11 ( 5 ) : 1835-1841.
  • 7高宝莲,王东林.CXCL12/CXCR4在胶质瘤侵袭性生长中的作用[J].临床与实验病理学杂志,2007,23(6):714-716. 被引量:5
  • 8Rubin JB, Kung AL, Klein RS, et al. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors[J]. Proc Natl Acad Sci USA,2003,100 (23):13513-13518.
  • 9Venkatesan S, Rose JJ, Lodge R, et al. Distinct mechanisms of agonist-induced endocytosis for human chemokine receptor CCR5 and CXCR4[J]. Mol Biol Cell, 2003.14(8): 3305-3324.
  • 10Orsini MJ, Parent JL, Mundell SJ, et al. Trafficking of the HIV coreceptor CXCR4 ,role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization [J]. J Biol chem, 1999,274(43):31076- 31086.

二级参考文献80

共引文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部