摘要
产单核细胞李斯特菌常引起新生儿、孕产妇、老年人和免疫抑制者患菌血症和脑膜炎。其血流感染发病率低,但病死率很高,病原学诊断复杂。本文报道1例以聚合酶链反应方法确诊的产单核细胞李斯特菌血流感染,以提高临床微生物学工作者对该病原菌生物学特性和实验室检测方法的认识。
Listeria monocytogenes （LM） is an important pathogen causing bacteremia and meningoencephalitis among newborns, pregnant women, the elderly, and immunosuppressed patients. Low incidence but high mortality characterizes a bloodstream infection caused by LM. Isolation and identification of LM are not easy in the clinical microbiology laboratory. In the present paper, a case of LM blood infection is presented, which was diagnosed rapidly by amplifying plfA gene through polymerase chain reaction in addition to traditional microbiological assays.
出处
《微生物与感染》
2009年第4期228-230,240,共4页
Journal of Microbes and Infections
基金
江苏省实验诊断学重点实验室基金(XK200731)
关键词
产单核细胞李斯特菌
血流感染
聚合酶链反应
Listeria monocytogenes
Bloodstream infection
Polymerase chain reaction
