脑转移瘤的磁共振成像新进展

New advances in magnetic resonance imaging of brain metastasis

脑转移瘤(BM)的生长需要适宜的微环境,而正常脑微环境的改变是MR探查BM的基础。利用局部磁场的变化,外加对比剂人为提高组织的差异,MR可准确发现脑转移瘤发生的部位、大小、数目和形态,而MR增强检查是诊断脑转移瘤的首选方法。各种MR新成像技术、扫描序列以及新型细胞内对比剂的应用,不仅可以进一步提高瘤灶检出率,还可提高敏感性,有利于制定合理的治疗方案,延长生存期。本文综述脑转移瘤的微环境、磁共振成像新技术方面的研究进展。

The growth of brain metastasis needs appropriate microenvironment,and the change of normal brain microenvironment is the basis for exploring metastasis with MRI.Through the local magnetic field changes and the application of contrast agents for improving the discrepancy of the cerebral tissue,MR can accurately detect brain metastasis in position,number,size,and shape.MR with contrast-enhanced technique is the first choice for screening brain metastasis.The application of all kinds of new MR techniques,sequences and intracellular contrast agents can not only further improve the specificity of detection,but also improve the sensitivity of MRI,which is favorable to formulating reasonable treatment and prolonging the lifetime of the patients.The microenvironment of brain metastasis and advances in the new MR techniques were reviewed in this article.