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生存素(survivin)在肝癌治疗中的研究进展 被引量:3

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摘要 生存素(survivin)是近年发现的一种凋亡抑制蛋白(inhibitor of apoptosis protein,IAP)家族成员,仅特异性地表达于肿瘤组织。survivin基因治疗具有良好的靶向性、特异性及安全性。survivin反义核酸具有抑制癌基因表达异常或诱导肿瘤细胞凋亡的作用,可以促进肿瘤细胞凋亡并抑制其增殖,而对正常组织几乎没有不良影响。
作者 秦安 王彤
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2009年第12期951-953,共3页 Chinese Journal of Hepatobiliary Surgery
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  • 1Wang W, Xu G L, Jia W D, et al. Ligation of TLR2 by versican: a link between inflammation and metastasis[J ]. Arch Med Res, 2009, 40(4): 321.
  • 2Du W W, Yang B B, Shatseva T A, et al. Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling [ J ]. PLoS One, 2010, 5(11): e13828.
  • 3Ju H, Lira B, Kim M, et al. Genetic variants A1826H and D2937Y in GAG - beta domain of versican influence susceptibility to intestinal- type gastric cancer[J]. J Cancer Res Clin Oncol, 2010, 136(2): 195.
  • 4Cattaruzza S, Schiappacassi M, Kimata K, et al. The globular domains of PG-M/versican modulate the proliferation - apop - to.sis equilibrium and invasive capabilities of tumor cells [J]. FASEB J, 2005, 18(6): 779.
  • 5Kischel P, Waltregny D, Dumont B, et al. Versican overexpression in human breast cancer lesions: known and new isoforms for stromal tumor targeting[J]. Int J Cancer, 2010, 126(3) : 640.
  • 6Riceiardelli C, Sakko A J, Ween M P, et al. The biological role and regulation of versiean levels in cancer [ J ]. Cancer Melastasis Rev, 2009, 28( 1 - 2) : 233.
  • 7Kim S, Takahashi H, Lin WW, et al. Carcinoma - produced factors activate myeloid cells through TLR2 to stimulate metastasis[J]. Nature, 2009, 457(7225): 102.
  • 8Domenzain - Reyna C, Hemdndez D, Miquel - Serra L, et al. Structure and regulation of the versican promoter: the versican promoter is regulated by AP - 1 and TCF transcription factors in invasive human melanoma cells [ J ]. J Biol Chem, 2009, 284(18): 12306.
  • 9Wang W, Xu G L, Jia W D, et al. Ligation of TLR2 by versican: a link between inflammation and metastasis[J ]. Arch Med Res, 2009. 40(4): 321.
  • 10Wang W,Xu GL,Jia WD,et al.Ligation of TLR2 by versican:a link between inflammation and metastasis[J]. Arch Med Res,2009,40:321-323.

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