白内障摘除术后不同后囊膜混浊的发生率和分布(英文)

Frequency and distribution of various posterior capsular opacities post cataract extraction

目的:评价院内白内障手术和人工晶状体(IOL)植入术后不同类型PCO的频率和分布。方法:本横断、观察和描述性研究包括200名2003/2007年间提交白内障手术的患者。男123名,女77名,年龄43～77(平均62.4)岁之间。患者平均随访期为23(16～60)mo。随访期间通过一份问卷收集数据并使用SPSS软件输入计算机。使用方差分析和卡方检验分析。结果:不同类型的后囊膜混浊,包括纤维化(63%),残留上皮细胞增殖(15%)和混合型(22%)。由PCO引起的视力减退发生的平均时间为19.3(3～48)mo。年轻患者白内障手术后视力明显提高(P=0.0001),但PCO的发生率也多些。在老年组,纤维化后囊膜混浊明显多见,而混合型混浊是最不普遍的(P=0.016)。结论:目前的研究并没有测定PCO发生的任何特定的危险因素,最常见的类型是纤维化。所有的病例都经历定性和定量的视力减退,其中一些需要YAG激光晶状体囊膜切开术治疗,比较昂贵并有其自身的并发症。

AIM： To evaluate the frequency and distribution of various types of post cataract surgery and intraocular lens （IOL） implantation posterior capsular opacity （PCO） in hospitals. METHODS： This cross sectional, observational and descriptive study included 200 patients, 123 male and 77 female aged between 43 and 77 （mean age 62.4） years, referring for cataract procedure from 2003 till 2007. The mean follow-up period of patients was 23 （ range from 16 to 60） months. Data were gathered during follow-up time via a questionnaire and entered in a computer using SPSS software. Analysis was performed using ANOVA and Chi- Square tests. RESULTS： The various types of PCO included, fibrotic （63%）, residual epithelial proliferative cells （15%） and mixed type （22%）. The mean time period for development of postoperative decreased visual acuity due to PCO was 19. 3 （range from 3 to 48） months, younger patients had a significantly better vision post cataract surgery （P= 0. 0001 ）, but the incidence of PCO was also more in them. In the older age group, fibrotic PCO was significantly more, while mixed type of opacities were the least prevalent （ P= 0. 016）. CONCLUSION ： The present study did not determine any specific risk factors for development of PCO, and the most common type was fibrosis, all of the cases experienced both qualitative and quantitative decrease in vision and some of them required treatment with YAG Laser capsulotomy which is relatively expensive and has its own complications.