摘要
目的:评价早期新鲜羊膜移植术治疗眼部重度碱烧伤的疗效。方法:对48例67眼重度碱烧伤患者按就诊时间分为A,B两组,烧伤0.5h~7d(包括7d)就诊者26例38眼(A组);烧伤7~20d(不包括7d)就诊者22例29眼(B组)。两组均采用新鲜羊膜移植术,术后均配戴软性角膜接触镜。3mo后观察眼表状况。结果:A组:角膜全透明者28眼,半透明者5眼,全混浊者3眼,角膜白斑者2眼,睑球粘连者2眼,有新生血管者2眼,视力≥0.4者28眼,<0.4者10眼;B组:角膜全透明者12眼,半透明者7眼,全混浊者6眼,角膜白斑者4眼,睑球粘连者13眼,有新生血管者15眼,视力≥0.4者11眼,<0.4者18眼。两组结果比较均有统计学意义(P<0.05)。结论:早期新鲜羊膜移植术可以更好的重建眼表,提高视力,是眼部重度碱烧伤的最佳治疗方法。
AIM: To evaluate the early stage of fresh amniotic membrane transplantation for treatment of severe ocular alkali burn.
METHODS: Forty-eight cases of 67 eyes with severe alkali burns were divided into A, B groups according to visiting time, 26 cases of 38 eyes burned for 0.5 hours -7 days (including 7 days) were treated for the A group; 22 cases of 29 eyes burned for 7-20 days (not including 7 days) were treated for the B group, both groups were transplanted with fresh amniotic membrane and wore soft contact lenses after operation. The ocular surface conditions and visual acuity were observated after 3 months.
RESULTS: There were 28 eyes of full transparent cornea, 5 eyes of semi-transparent, 3 eyes of all muddy and 2 eyes of corneal leukoplakia, and 2 eyes of symblepharon, and 2 eyes of new blood vessels,and the visual acuity of 28 eyes was ≥0.4, 10 eyes 〈0.4 in A group. There were 12 eyes of full transparent cornea, 7 eyes of semi-transparent, 6 eyes of all muddy and 4 eyes of corneal leukoplakia, and 7 eyes of symblepharon, and 15 eyes of new blood vessels, and the visual acuity of 11 eyes was ≥0.4, 18 eyes 〈0.4 in B group. Comparison of the two groups were statistically significant (P〈0.05).
CONCLUSION: Early fresh amniotic membrane transplantation could be better for reconstruction of ocular surface and improving vision, it is the best therapeutic approach for the severe ocular alkali burns.
出处
《国际眼科杂志》
CAS
2010年第1期129-130,共2页
International Eye Science
关键词
早期
新鲜羊膜移植
重度
碱烧伤
early
fresh amniotic membrane trans-plantation
severe
alkali burn