3种方案治疗老年性肺炎的成本-效果分析

Pharmacoeconomic evaluation of three therapeutic regimens for senile pneumonia

目的:探讨不同药物的治疗方案对同一疾病所产生的经济效果。方法:采用回顾性研究方法,对经确诊为老年性肺炎的住院患者115例,根据治疗方案不同分为3组,A组:头孢呋辛+左氧氟沙星;B组:头孢地嗪;C组:头孢派酮舒巴坦。应用药物经济学成本-效果分析法进行比较。结果:A,B,C组成本依次为3073.46元,4248.96元,4955.89元,有效率分别为84.6%,85.0%,86.1%,敏感性分析结果均与参数改变前的结果基本一致。结论:A组治疗方案优于B组、C组。

Objective ： To analyze pilarmacoeconomics of therapeutic regimens of different drugs in the management of the same disease, senile pneumonia. Methods： In a retrospective study, a total of 115 patiens with senile pneumonia were enrolled and divided into 3 groups according to their therapeutic regimens：cefuroxime ＋ levofloxa- cin （ group A） , cefodizime （ group B ） , and cefoperazone ＋ sulbactam （ group C）. The therapeutic effects were compared by the cost-effectiveness analysis method. Results： The costs were RMB 3073.46, 4248.96 and 4955. 89 Yuan, and the effective rates were 84.6% , 85.0% and 86.1% ,respectively,in groups A, B and C. The results of sensitivity analysis were consistent with the described results. Conclusion： In pharmaeoeconomics, the therapeutic regimen of cefuroxime ＋ levofloxacin is superior to those of cefodizime and cefoperazone ＋ sulbactam.