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联用小剂量二甲双胍治疗代谢性高血压22例疗效观察

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摘要 目的:观察联用小剂量二甲双胍治疗代谢性高血压的治疗效果。方法:选择高血压患者22例,所有患者均在抗高血压三联(吲哒帕胺、依那普利、硝苯地平缓释片或美托洛尔)治疗及积极生活方式干预(锻炼、低脂低盐饮食、控制体重)的基础上,加服二甲双胍。观察2个月,比较治疗前后患者的血压、血脂及BMI变化。结果:与治疗前相比,平均收缩压和舒张压分别下降19.1mmHg和11mmHg,两者差异有显著性(P<0.05);BMI下降1.3kg/m^2,差异有显著性(P<0.05);甘油三酯下降0.23mmol/L,差异有显著性(P<0.05)。其他指标如TC、LDL-C均有下降,HDL-C有升高,但差异无显著性(P>0.05)。结论:对代谢性高血压患者在常规抗高血压治疗及积极生活方式干预(锻炼、低脂低盐饮食、控制体重)的基础上,加服二甲双胍治疗不但可取得较好的降压效果,而且对改善血脂代谢及控制体重亦有一定效果。
作者 刘妍 王建生
出处 《中国社区医师(医学专业)》 2009年第23期43-43,共1页
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