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阿奇霉素联合头孢丙烯治疗儿童上呼吸道感染的疗效分析

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摘要 目的:评价阿奇霉素联合头孢丙烯治疗儿童上呼吸道细菌性感染的疗效和安全性。方法:采用随机双盲对照的方法,分3组,每组40例,A组口服抒罗康,B组口服施复捷,C组口服抒罗康和施复捷。结果:A组(抒罗康组)总有效率77.5%,不良反应发生率5%。B组(施复捷组)总有效率80%,不良反应发生率5%。C组总有效率95%,不良反应发生率7.5%。均未因不良反应而中断治疗。A组与B组之间疗效比较,x^2=0.08,P>0.05,差异无显著性;A组与C组之间疗效比较,x^2=5.16,P=0.023,差异有显著性;B组与C组之间疗效比较,x^2=4.11,P=0.0425,差异有显著性。C组不良反应发生率与A组或B组比较(A组和B组的不良反应发生率相同),x^2=0.17,P>0.05,差异无显著性。结论:阿奇霉素治疗儿童上呼吸道细菌性感染有效,头孢丙烯治疗儿童上呼吸道细菌性感染有效,阿奇霉素联合头孢丙烯治疗儿童上呼吸道细菌感染疗效更好,优于单药给药,不良反应并未因联合治疗而增多,安全性好。
作者 刘远姝 朴丽
出处 《中国社区医师(医学专业)》 2009年第24期126-127,共2页
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