摘要
以钛酸正丁酯(Cl6H36TiO4)为原料,采用溶胶-凝胶法制备了TiO2薄膜。TiO2薄膜分别在300,400,500,600,800℃下于空气中热处理2h。将热处理前后的TiO2薄膜浸泡于模拟体液(simulated body fluids,SBF)中,考察其表面诱导类骨磷灰石形成的能力。利用X射线衍射、扫描电子显微镜、能谱仪、Fourier变换红外光谱等测试手段表征TiO2薄膜和磷灰石的微观结构。结果表明:原始和经300℃热处理的TiO2薄膜为无定形结构;随着煅烧温度的升高,TiO2由无定形结构向锐钛矿相转变;温度升高至800℃后,锐钛矿相完全转化为金红石相。TiO2薄膜经SBF浸泡7d后,经400,500,600,800℃热处理的TiO2薄膜表面生成含有碳酸根的羟基磷灰石,且其Ca与P的摩尔比为1.52,接近人体骨骼的钙磷比(1.67)。而原始和经300℃热处理的TiO2薄膜无此现象发生,这说明TiO2薄膜的晶型对其生物活性具有重要影响,锐钛矿和金红石相TiO2薄膜均具有诱导磷灰石生成的能力。
Titania (TiO2) thin films were deposited using tetrabutylorthotitanate (Cl6H36TiO4) as a starting material by a sol-gel method.The as-deposited TiO2 films were annealed at 300,400,500,600 and 800 ℃ for 2h in atmosphere,respectively.The as-deposited and annealed TiO2 films were soaked in simulated body fluids (SBF) to investigate the formation of bone-like apatite on the surfaces.The effect of anneal temperature on the phase composition and the bioactivity of TiO2 films were investigated by X-ray diffraction,scanning electron microscopy,energy-dispersive X-ray spectrometry and Fourier transform infrared spectroscopy.The results indicate that the as-deposited TiO2 film and TiO2 films annealed at 300 ℃ are amorphous.The phase compositions of TiO2 films transformed from anatase to rutile when the anneal temperature increased.The phase composition of TiO2 film annealed at 800 ℃ are mainly composed of rutile.The carbonate-containing hydroxyapatite could be induced on the surface of TiO2 film annealed at 400,500,600 ℃ and 800 ℃ during the SBF immersion test.However,the as-deposited TiO2 film and the TiO2 film annealed at 300 ℃ has no bioactivities.The bioactivity of the TiO2 film depends on the phase composition.The anatase and rutile formed in the films both possess an excellent bioactivity.
出处
《硅酸盐学报》
EI
CAS
CSCD
北大核心
2010年第1期148-152,共5页
Journal of The Chinese Ceramic Society
基金
江苏省自然科学基金(BK2008541)资助项目