与帕金森病相关的临床误诊分析

Misdiagnoses Related to Parkinson's Disease

目的分析与帕金森病相关误诊患者的临床资料,以期提高临床医生对该病的认识水平,提高帕金森病的正确诊断率。方法利用兰州大学第二医院运动障碍疾病数据库筛选出26例误诊患者,结合国内外的参考文献以系统回顾的方法分析疾病误诊原因。结果特发性震颤、血管性帕金森综合征、脑血管病、进行性核上性麻痹、药物性帕金森综合征、多系统萎缩等疾病易与帕金森病相混淆。结论病史采集不详细、体格检查不仔细、过分依赖实验室检查或缺少必要的实验室检查、对PD认识不足等因素与帕金森病相关误诊有关。

Objective To analyze the clinical data of misdiagnoses related to Parkinson＇s disease, to improve the awareness level of clinical doctors and the rate of correct diagnoses of Parkinson＇s disease. Methods Twenty - six misdiagnosed patients screened out from Dyskinesia Disease Database of Second Hospital of Lanzhou University. The misdiagnoses reasons were analyzed retrospectively integrating with references at home and abroad. Results Parkinson＇s disease were easily confused with idiopathic tremor, vascular Parkinson＇s disease, cerebrovascular disease, progressive supranuclear palsy, drug- induced par- kinson＇s syndrome, multiple system atrophy, etc. Conclusion Not detailed history collection, careless physical examinations, over - reliance on laboratory tests or lack of necessary laboratory tests and of PD knowledge and other factors are related to misdi- agnoses of Parkinson＇s disease.