摘要
帕金森病又称震颤麻痹,是中老年人最常见的中枢神经系统变性疾病。主要是因位于中脑部位"黑质"中的细胞发生病理性改变后,多巴胺的合成减少,抑制乙酰胆碱的功能降低,则乙酰胆碱的兴奋作用相对增强。两者失衡的结果便出现了"震颤麻痹"。短时间、一次性的高血糖对人体无严重损害,然而长期的高血糖会使全身各个组织器官发生病变,导致急慢性并发症的发生。众多研究显示高血糖可能与帕金森病有关,本文就高血糖与帕金森病的关系进行综述。
Parkinson＇s disease, also known as paralysis agitans, is the most common degenerative diseases of the cen- tral nervous system in elderly. Its main reason is that dopamine synthesis and the function inhibiting acetylcholine are reduced, while the excitatory effect of acetylcholine relatively enhanced after the pathological changes of cells in substantia nigra of Pars mesencephalica. The imbalance between them results in ＂ Shaking Palsy＂. Short time or one - time hyperglycemia is of no seri- ous damage to human body, but the long - term would cause lesions in various tissues and organs, leading to acute or chronic complications. Many studies show that hyperglycemia may be related to Parkinson＇s disease. This article reviews the relationship of hyperglycemia to Parkinson＇s disease.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第2期210-212,共3页
Chinese General Practice
关键词
帕金森病
糖尿病
高血糖症
Parkinson＇s disease
Diabetes mellitus
Hyperglycemia
