舒林酸对老年高血压病人常用降压药疗效的影响

The influence of therapeutic effect of sulindac to the senile hypertensive patients with hypotensor

目的:观察舒林酸对老年高血压病人常用降压药疗效的影响,方法:退行性骨关节炎合并高血压病的老年病人32例,男性26例,女性6例,平均年龄(77.8±7.3)a,在长期服用降压药氨氯地平、吲达帕胺、依那普利时给予舒林酸200mng bid po,治疗退行性骨关节炎,在服舒林酸3h后测定BP,并对照服舒林酸前10d同时间BP平均值,观察舒林酸对BP的影响,结果:舒林酸治疗32例退性骨关节病人有效率达96.8%,且对BP无影响,结论:服用舒林酸不影响常用降压药对老年高血压病人的疗效.

AIM:To observe the effect of the sulindac to hypotensor which senile patients often take. METHODS: Thirty-two senile patients suffered from degenerative osteoarthritis combined with hypertension(M26,F6,average age 77. 8±7. 3)adminstrated with hypotensor were given sulindac 200mg bid po,to treat the degenerative osteoarthritis. The blood pressure was measured 3h after adminstration of the sulindac. Comparing the blood pressure with the average blood pressure 10d before use of sulindac,the effect of the sulindac to the blood pressure was observed. RESULTS: The effective rate of sulindac in treating senile patients' arthritis was 96.8%,while there was no significant change of blood pressure after administration of sulindac. CONCLUSION t Adminstration of the sulindac will not affect the treatment effect of the hypotensor to the senile patient with hypertension.