细胞因子与化疗药物交替灌注治疗非小细胞肺癌(附68例报告)

Effect of Bronchial Artery Infusion with Anticancer Agents and Cytokines for Non Small Cell Lung Cancer

将６８例经病理学证实的中晚期非小细胞肺癌（ＮＳＣＬＣ）患者随机分为Ａ、Ｂ两组，分别进行经留置导管支气管动脉内交替灌注化疗药物及细胞因子和单纯支气管动脉灌注（ＢＡＩ）治疗３～４次。结果表明，Ａ、Ｂ两组的近期有效率分别为９１１８％和４４１２％，二者具有显著性差异，无严重并发症。由此证明，留置导管及细胞因子与ＢＡＩ的有机配合，为中晚期ＮＳＣＬＣ的治疗提供了一种新的。

To evaluate the effect of bronchial artery infusion (BAI) with anticancer agents and cytokines via indwelling catheter for advanced non small cell lung cancer (NSCLC),68 patients with advanced primary NSCLC,which were proved by the pathology,were randomly divided into two groups of 34 patients each.The two groups were given BAI with anticancer agents and cytokines via indwelling catheter and single BAI for 3 to 4 times respectively.The results showed that the efficiencies of the two groups were 91.18% and 44.12%,there were significant difference between the two groups by χ 2 test ( P <0.05) and there were not serious complications.It is a new,effective therapy in treatment of BAI with anticancer agents and cytokines via indwelling catheter for advanced NSCLC.