摘要
为解决辐射致癌患者的赔偿问题,美国国立卫生研究院提出用病因概率(probability of causation,PC)来评估癌症和所受电离辐射之间的关联程度,我国也发布了根据PC判断放射性肿瘤的相关国家标准。本文总结了与PC计算相关的辐射致癌超额危险模型的研究进展,并介绍了超额危险在不同人群之间的转换方法、与低剂量和低剂量率的依赖关系、其他流行病学危险因子的修正方法以及PC的应用情况。
Probability of causation （PC） was used to facilitate the adjudication of compensation claims for cancers diagnosed following exposure to ionizing radiation.In this article,the excess cancer risk assessment models used for PC calculation are reviewed.Cancer risk transfer models between different populations,dependence of cancer risk on dose and dose rate,modification by epidemiological risk factors and application of PC are also discussed in brief.
出处
《军事医学科学院院刊》
CSCD
北大核心
2009年第6期570-573,共4页
Bulletin of the Academy of Military Medical Sciences
关键词
肿瘤
辐射性
病因概率
超额危险
危险因素
neoplasms
radiation-induced
probability of causation
excess risk
risk factors
