尿酸结石的诊断及其溶石治疗

Diagnosis and dissolution therapy of uric acid calculi

报告１９８４年１２月～１９９５年１２月对纯尿酸结石病人１７例的治疗经验。诊断标准：（１）ＫＵＢ阴性，（２）ＩＶＵ或逆行尿路造影见到充盈缺损，（３）Ｂ超或ＣＴ证实该充盈缺损系结石所致。尿酸碱化治疗在早期病人采用苏打片，后期病人选用枸橼酸钾，调节药物剂量使尿ｐＨ值维持在６８左右。尿酸结石导致急性梗阻性无尿亦可试作溶石治疗。

The diagnostic criteria for pure uric acid calculi were as follows:(1)KUB being negative,(2) a definite filling defect in the urinary tract on intravenous or retrograde urography and (3) B ultrasonography or CT confirmed the presence of the defect resulted from stone.Urine alkalization with sodin bicarbonate in early cases and potassium citrate in late cases was conducted for 17 patients.The dosage was adjusted so as to make the urine pH around 6.8.Patients with acute obstructive anuria due to uric acid stones were also candidates of dissolution therapy.All the 17 patients including two with obstructive anuria were cured by means of oral alkalization therapy.