原发性降结肠恶性黑色素瘤1例

Diagnosis and treatment of primary malignant melanoma in the descending colon:a report of one case

恶性黑色素瘤是一种来源于皮肤移行区交界痣黑色素细胞的高度恶性肿瘤,早期即发生血液或淋巴结转移,预后差.肛管直肠是仅次于皮肤及眼睛的第三好发部位,结肠原发性恶性黑色素瘤临床上罕见.本例患者在行根治性切除及淋巴结清扫手术后确诊结肠原发性恶性黑色素瘤,术后行全身化疗及生物免疫治疗效果佳,随访5年患者生存.

Malignant melanoma arises from melanocytes. As blood or lymph node metastasis occurs in the early stage of malignant melanoma, the disease has a poor prognosis. The anorectum, behind the skin and eyes, is the third most frequent site of malignant melanoma. Primary malignant melanoma of the colon is a rare clinical condition. Here, we report a case of primary malignant melanoma in the colon in a 66-year-old female. She was definitely diagnosed as primary malignant melanoma in the descending colon after radical resection and lymph node dissection. Postoperative systemic chemotherapy and immunotherapy achieved good effects. The patient is still alive five years postoperatively.