新型微生态益生菌凝结芽孢杆菌研究进展

Research Advances of Novel Microecologic Probiotics Bacillus coagulans

凝结芽孢杆菌(Bacillus coagulans)是近年来益生菌领域的后起之秀,其除具有乳酸菌和双歧杆菌等保健功效外,还具有耐高温、耐酸和耐胆盐等高抗逆性,且具有较强的抑制肠道致病菌能力。在国外已广泛应用于保健、医疗、食品和畜牧等领域,但在我国关于凝结芽孢杆菌的研究和开发起步不久,而且发展缓慢。本文从凝结芽孢杆菌特性、益生作用及机理、发酵培养和临床研究方面概括和总结国内外的研究进展。

Bacillus coagulans,which belongs to Bacillus and exerts similar function to Bacillus acidi lactici and Bacillus bifidus in healthcare,is characterized by strong resistance to heat,acid and bile salt.In addition,it has capabilities of inhibiting pathogenic bacteria in intestine.Bacillus coagulans has been applied in many aspects of healthcare,medicine,food and prologue abroad.Although the research and development on Bacillus coagulans have carried out for about ten years at home,the level falls behind in the world.In this paper,the characteristics,probiotic mechanisms,fermentation performance and clinical research of Bacillus coagulans are summarized in detail.